Stan Weiner, M.D., F.A.C.C. - Professional Research

Principal Investigator

INVESTIGATIONAL DEVICE TRIALS

• RESET – Restoration of Chronotropic Competance in Heart Failure Patients with Normal Ejection Fraction (Boston Scientific)
• CHAMPION – CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in NYHA Class III Heart Failure Patients (CardioMEMS)
• FIX-HF-5 - Evaluation of the Safety and Efficacy of the OPTIMIZER™ System with active Fixation Leads in Subjects with Heart Failure Resulting from Systolic Dysfunction (Impulse Dynamics)
• EASYTRAK 3 DOWNSIZE – Guidant Lead 4591/4592/4593 Clinical Study (Guidant)
• EASYTRAK 4 - EASYTRAK® 4 STEERABLE LV Coronary Venous Bipolar Pace/Sense Lead (Guidant)
• EXACT – Examination of Arrhythmia Classification and Therapy (Guidant)
• ATTRAC – Arrhythmia Treatment with a Thermocouple Radiofrequency Ablation Catheter (Stereotaxis)
• ATTRAC II – Arrhythmia Treatment with a Thermocouple Radiofrequency Ablation Catheter – Remote Protocol (Stereotaxis)

OTHER DEVICE TRIALS

• LSR – Longitudinal Surveillance Registry (Boston Scientific)
• LONGITUDE – Long Term Information and Technology Update
• RATE – Registry of AT/AF Episodes in the CRM Device Population(St. Jude Medical)
• PEGASUS CRT – Pacing Evaluation – Atrial Support Study in Cardiac Resynchronization Therapy (Guidant)
• REFLEx – ENDOTAK RELIANCE® G Evaluation of Handling and Electrical Performance (Guidant)
• CRT RENEWAL – Cardiac Resynchronization Therapy Registry Evaluating Patient Response with RENEWAL Family Devices (Guidant)
• ASPEN-ICD – AF Suppression Pacing to Prevent first Episode of Atrial Fibrillation in High Risk Patients with an Implantable Cardioverter Defibrillator (St. Jude Medical)
• HRV-CONTAK® RENEWAL™ - Heart Failure Rate Variability Registry (Guidant)
• INTRINSIC RV – Inhibition of Unnecessary RV Pacing with AV Search Hysteresis in ICDs (Guidant)
• SMART AV – SMARTDELAY determined AV Optimization: A Comparison to Other AV Delay Methods Used in Cardiac Resynchronization Therapy
• APPROPRIATE – Assessment of Proper Physiologic Response with Rate Adaptive Pacing Driven by Minute Ventilation or Accelerometer
  

DRUG TRIALS

• RELY – Randomized Evaluation of Long Term Anticoagulation Therapy - Comparing the Efficacy and Safety of Two Blinded Doses of Dabigatran Etexilate with Open Label Warfarin for the Prevention of Stroke and Systemic Embolism in Patients with Non-Valvular Atrial Fibrillation: Prospective, Multi-Center, Parallel-Group, Non-Inferiorty Trial (Boehringer-Ingelheim)
• RELY-ABLE - Longterm Multi-Center Extension of Dabigatran Treatment in Patients with Atrial Fibrillation Who Completed the RE-LY Trial and a Cluster Randomized Trial to Assess the Effect of a Knowledge Translation Intervention on Patient Outcomes

• ARISTOTLE – A Phase 3 Active (Warfarin) Controlled, Randomized, Double-Blind, Parallel-Arm Study to Evaluate Efficacy and Safety of Apixaban in Preventing Stroke and Systemic Embolism in Patients with Nonvalvular Atrial Fibrillation
  

Co-Investigator

• SAVE PACe – Search AV Extension for Promoting Atrioventricular Conduction (Medtronic)
• RESTORE-US – Registry of Cardiac Resyncronization Therapy-US (Medtronic)
• ASSESS – Assessment of Unipolar vs. Bipolar Pacing Thresholds (Guidant)
• LSR-ASL – Longitudinal Surveilance Registry – Acuity Spiral Lead (Boston Scientific)

• Shock-Less – (Medtronic)